Int J Biol Sci ; 10 2: How to cite this article: The recognition does not require specific accessory cells, antigen uptake, antigen processing, or MHC class I, class II, or class Ib expression. This subset of T cells plays important roles in mediating innate immunity against a wide variety of infections and displays potent and broad cytotoxic activity against human tumor cells.
Desired Reconstitution Concentration Background: It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism 1, 2.
Human TNF-alpha consisits of a 35 amino acid aa cytoplasmic domain, a 21 aa transmembrane segment, and a aa extracellular domain ECD 3. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells 1, 2.
TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface 4. Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I 2, 5.
Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Showing 1 - 10 Filter your results:Chemotaxis (from chemo-+ taxis) is the movement of an organism in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment.
This is important for bacteria to find food (e.g., glucose) by swimming toward the highest concentration of food molecules, or to flee from poisons. Measured in a cytotoxicity assay using L‑ mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D.
and M.L. Neale () in Lymphokines and Interferons, A . Browse our catalog of related publications to learn how Biomark from Fluidigm empowers researchers across a range of genomic fields.
Upregulation of CXCR2 in tumor cells has been documented in several types of cancer. As one of its ligands, CXCL5 is associated with neutrophil infiltration and . The first substrate in the table, MHC class I-related chain A and B protein, is a costimulator for cytokine production  and was shown to be processed by ADAM10 and ADAM17 using small molecule inhibitors and siRNA treatments [21, 22].It triggers natural killer cells and .
Phototropism is the growth response of a plant in response to light direction. Different parts of a plant exhibit different reactions to light. Different parts of a plant exhibit different reactions to light.